Coenzyme Q10 in health and disease is the title of the new Q10 book from Prof. Dr. Anna Gvozdjáková, Ph.D., DSc. From the Medical Faculty of Comenius University in Bratislava/Slovakia.  The book is in the Slovak language. 

This is only 2 years after her previous book in English: Recent Advances in Mitochondrial Medicine and Coenzyme Q10. 

Anna Gvozdjáková has cooperated with the discoverer of coenzyme Q10, Professor Frederick Crane. Professor Gvozdjáková’s findings of the beneficial effect of coenzyme Q10 in children with autism led Professor Crane to the hypothesis of a new function of coenzyme Q10 in mitochondria and about its transport across the outer membrane of mitochondria.

Anna Gvozdjáková has also worked on many projects with Dr. Raj K. Chopra, President of Tishcon Corp. in the USA. Tishcon supported at least 13 projects in the field of mitochondrial function of Q10 in clinical and experimental studies and provided different types of coenzyme Q10 and ubiquinol formulations.

During my time at Kaneka, I was her key scientific contact for clinical studies with Kaneka Ubiquinol

Ubiquinol talk with Prof. Dr. Anna Gvozdjáková
Ubiquinol talk with Prof. Dr. Anna Gvozdjáková

Coenzyme Q10 in health and disease: contents and acknowledgments

The 2020 book: Coenzyme Q10 in Health and Diseases

Anna Gvozdjáková, Jarmila Kucharská, Zuzana Sumbalová

Publisher: HERBA, s.r.o., Bratislava, Slovakia, 2020, pp.157.

Contents

  1. Frederick Loring Crane – discoverer of coenzyme Q10
  2. History of discovery and perspective of coenzyme Q10
  3. Characteristics of coenzyme Q10
  4. Diagnostic significance of coenzyme Q10 determination
  5. Diagnostic significance of measuring mitochondrial bioenergetics in patients
  6. Coenzyme Q10 in health and disease
  7. Metabolic non-communicable diseases
  8. Importance of coenzyme Q10 in cardiovascular diseases
  9. Statins and coenzyme Q10
  10. Importance of coenzyme Q10 in oncological diseases
  11. Significance of coenzyme Q10 in patients with kidney disease
  12. Significance of coenzyme Q10 in patients with diabetes mellitus
  13. Aging and coenzyme Q10
  14. Alzheimer’s disease and coenzyme Q10
  15. Significance of coenzyme Q10 in children with autism
  16. Significance of coenzyme Q10 in patients with fertility disorders
  17. Influence of polarized light on coenzyme Q
  18. Influence of molecular hydrogen on oxidative stress, coenzyme Q and mitochondria
  19. The effect of complete starvation on the body
  20. The effect of ketogenic and high-protein diet on obesity, antioxidants and oxidative stress
  1. Influence of natural mineral water on coenzyme Q and mitochondria
  2. Influence of seasonal variations on antioxidants, oxidative stress and mitochondria
  1. Influence of Sun and Moon on oxidative phosphorylation and coenzyme Q.
  2. Influence of antioxidants on skin cell regeneration
  3. Hypothesis: SARS-CoV-2 target virus may be mitochondrial bioenergetics and coenzyme Q10
  1. Active participation of authors in conferences on coenzyme Q10.

Anna Gvozdjáková

Bratislava, 25.09.2020

Acknowledgments

Prof Anna Gvozdjáková compliments to Dr. Peter Lambrechts
Prof Anna Gvozdjáková compliments to Dr. Peter Lambrechts
Dr. Raj Chopra and Dr. Lambrechts acknowledged in the book
Dr. Raj Chopra and Dr. Lambrechts acknowledged in the book

Coenzyme Q10 and ubiquinol

See my contributions on Q10 and ubiquinol in the book on comparison of bioavailability of Q10 and ubiquinol and the dynamic equilibrium between both. 

Comparison of bioavailability of Q10 and ubiquinol
Comparison of bioavailability of Q10 and ubiquinol
Dynamic equilibrium between Q10 and ubiquinol
Dynamic equilibrium between Q10 and ubiquinol

In the meanwhile, I preliminary calculated that on average in one hour each Q10 molecule is recycled/reduced to ubiquinol about 2500 times in our mitochondria. 

Sick & unhealthy have a Q10 deficit compared to healthy people

I would like to conclude with following interesting findings from Professor Gvozdjáková in her multicenter Slovak Study (3000 human samples) showing that all groups of patients have a Q10 deficit compared to healthy volunteers. 

Sick and unhealthy have a Q10 deficit compared to healthy people
Sick and unhealthy have a Q10 deficit compared to healthy people